Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 12/20 | 0.38 |
| ▸ | HTR2A | P28223 | 9/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.38 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | ADH7 | P40394 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23997632 | 0.85 | KDM4E (0.47) | KDM4EALDH1A1HSD17B10SLC6A4HTR2A | |
| SCHEMBL23997711 | 0.81 | HPGD (0.39) | KDM4EALDH1A1HSD17B10SLC6A4ADH1B | |
| SCHEMBL22765684 | 0.81 | KDM4E (0.49) | KDM4EALDH1A1HSD17B10SLC6A4HTR2A | |
| SCHEMBL26568731 | 0.81 | P2RX7 (0.43) | KDM4EALDH1A1ADH1BADH1CADH1A | |
| SCHEMBL10565368 | 0.81 | ADH1B (0.37) | ALDH1A1HSD17B10ADH1BADH1CADH1A | |
| SCHEMBL5542553 | 0.80 | NPC1 (0.46) | KDM4EALDH1A1ADH1BADH1CADH1A | |
| SCHEMBL5545625 | 0.80 | KDM4E (0.50) | KDM4EALDH1A1ADH1BADH1CADH1A | |
| SCHEMBL21377286 | 0.79 | ADH1B (0.36) | KDM4EALDH1A1HSD17B10ADH1BADH1C | |
| SCHEMBL22854882 | 0.77 | HPGD (0.42) | KDM4EALDH1A1ADH1BADH1CADH1A | |
| SCHEMBL24249619 | 0.75 | SRC (0.57) | KDM4EALDH1A1HSD17B10SLC6A4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2922535-B1 | THROMBIN INHIBITORS | MERCK SHARP & DOHME (US) | 2021-11-10 | — | — | EP | disclosed |