SCHEMBL21377944

SCHEMBL21377944

N#Cc1c(-n2c3ccccc3c3cc(-c4ccccc4)ccc32)c(-n2c3ccccc3c3cc(-c4ccccc4)ccc32)c(-c2cccc(-n3c4ccncc4c4cnccc43)c2)c(-n2c3ccccc3c3cc(-c4ccccc4)ccc32)c1-n1c2ccccc2c2cc(-c3ccccc3)ccc21

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 1/20 0.36
PDE10A Q9Y233 6/20 0.33
MAOA P21397 4/20 0.33
MAOB P27338 4/20 0.33
DHODH Q02127 1/20 0.33
ACHE P22303 1/20 0.33
NPY5R Q15761 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
NCOA3 Q9Y6Q9 1/20 0.31
NRP1 O14786 1/20 0.31
MAPT P10636 1/20 0.31
TSPO P30536 1/20 0.30
CYP2D6 P10635 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21378077 0.94 CYP11B2 (0.40) CYP11B2PDE10AMAOAMAOBDHODH
SCHEMBL21377954 0.90 RXFP1 (0.35) CYP11B2PDE10AMAOADHODHKDM4E
SCHEMBL21378078 0.89 CYP11B2 (0.38) CYP11B2MAOAMAOBACHEKDM4E
SCHEMBL31273551 0.89 CYP11B2 (0.37) CYP11B2PDE10AMAOAMAOBDHODH
SCHEMBL21396825 0.88 CYP11B2 (0.38) CYP11B2PDE10AMAOAMAOBDHODH
SCHEMBL21378036 0.88 CYP11B2 (0.37) CYP11B2MAOAMAOBACHENPY5R
SCHEMBL21396871 0.87 CYP11B2 (0.37) CYP11B2PDE10ADHODHNPY5RKDM4E
SCHEMBL21396865 0.87 CYP11B2 (0.37) CYP11B2PDE10ADHODHNPY5RKDM4E
SCHEMBL21377920 0.86 KDM4E (0.45) KDM4EATML3MBTL1MAPTTSPO
SCHEMBL21481446 0.86 KDM4E (0.44) MAOAMAOBACHENPY5RKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11608333-B2 Composition of matter for use in organic light-emitting diodes KYULUX, INC. (JP) 2023-03-21 US disclosed
US-20190292181-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES Kyulux North America, Inc. 2019-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190292181-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES CRY2, SLCO1B3, NDUFV3 CYP11B2 1221/4885PDE10A 3833/4885MAOA 123/4885
US-11608333-B2 Composition of matter for use in organic light-emitting diodes CRY2, SLCO1B3, NDUFV3 CYP11B2 1221/4885PDE10A 3833/4885MAOA 123/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.