Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1862576 | 1.00 | TRPM8 (0.48) | TRPM8TRPA1EPHX1OPRM1ALDH1A1 | |
| SCHEMBL31152467 | 0.86 | TRPM8 (0.48) | TRPM8TRPA1EPHX1OPRM1ALDH1A1 | |
| SCHEMBL31148535 | 0.85 | TRPM8 (0.52) | TRPM8TRPA1EPHX1OPRM1ALDH1A1 | |
| SCHEMBL5114606 | 0.79 | TRPM8 (0.46) | TRPM8TRPA1EPHX1OPRM1ALDH1A1 | |
| Bicarbonate SCHEMBL1660906 | 0.79 | EPHX1 (0.47) | TRPM8TRPA1EPHX1ALDH1A1LMNA | |
| Water SCHEMBL30690409 | 0.79 | TRPM8 (0.48) | TRPM8TRPA1EPHX1OPRM1ALDH1A1 | |
| SCHEMBL28738013 | 0.77 | TRPM8 (0.47) | TRPM8TRPA1EPHX1ALDH1A1LMNA | |
| SCHEMBL4389935 | 0.77 | TRPM8 (0.65) | TRPM8TRPA1EPHX1ALDH1A1LMNA | |
| SCHEMBL13465301 | 0.77 | TRPM8 (0.65) | TRPM8TRPA1EPHX1ALDH1A1LMNA | |
| SCHEMBL11215068 | 0.76 | TRPM8 (0.42) | TRPM8TRPA1EPHX1OPRM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3383200-B1 | COMPOSITIONS | SYMRISE AG (DE) | 2019-11-06 | — | — | EP | claimed |
| US-20190289886-A1 | SUBSTANCE MIXTURES | SYMRISE AG (DE) | 2019-09-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190289886-A1 | SUBSTANCE MIXTURES | PNN, NISCH, HES1 | TRPM8 552/4885TRPA1 158/4885EPHX1 3257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.