Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5114606 | 0.83 | TRPM8 (0.46) | TRPM8TRPA1OPRM1EPHX1ALDH1A1 | |
| SCHEMBL5114601 | 0.83 | TRPM8 (0.42) | TRPM8TRPA1OPRM1EPHX1ALDH1A1 | |
| SCHEMBL7766491 | 0.81 | TRPM8 (0.40) | TRPM8TRPA1OPRM1EPHX1ALDH1A1 | |
| SCHEMBL27797531 | 0.80 | TRPM8 (0.42) | TRPM8TRPA1OPRM1EPHX1ALDH1A1 | |
| SCHEMBL5501055 | 0.78 | OPRM1 (0.47) | TRPM8TRPA1OPRM1EPHX1ALDH1A1 | |
| SCHEMBL1862576 | 0.76 | TRPM8 (0.48) | TRPM8TRPA1OPRM1EPHX1ALDH1A1 | |
| SCHEMBL21380098 | 0.76 | TRPM8 (0.48) | TRPM8TRPA1OPRM1EPHX1ALDH1A1 | |
| SCHEMBL4314193 | 0.75 | EPHX1 (0.43) | TRPM8TRPA1OPRM1EPHX1 | |
| SCHEMBL9850843 | 0.74 | OPRM1 (0.41) | TRPM8TRPA1OPRM1EPHX1ALDH1A1 | |
| SCHEMBL18473587 | 0.74 | ALDH1A1 (0.47) | TRPM8TRPA1OPRM1EPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4310443-A | ACTIVATORS OF METAL OXIDES OR CARBOXYLATES, METHACRYLATES, MALEIMIDES OR OXIMES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-01-12 | — | — | US | disclosed |