SCHEMBL21382869

SCHEMBL21382869

CC1(C)OB(c2ccc3c(c2)Oc2ccnc4cccc-3c24)OC1(C)C

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 9/20 0.38
LPL P06858 8/20 0.38
EGFR P00533 2/20 0.38
PRMT5 O14744 1/20 0.34
WDR77 Q9BQA1 1/20 0.34
KDM4E B2RXH2 1/20 0.33
MAPK1 P28482 1/20 0.33
ATM Q13315 1/20 0.33
IRAK4 Q9NWZ3 1/20 0.33
DGAT1 O75907 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31
PDGFRB P09619 1/20 0.31
KDR P35968 1/20 0.31
ALPL P05186 1/20 0.31
IDO1 P14902 1/20 0.30
TDO2 P48775 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21382887 0.89 LIPG (0.39) LIPGLPLEGFRDGAT1PDGFRB
SCHEMBL17776257 0.81 KDM4E (0.51) LIPGLPLEGFRPRMT5WDR77
SCHEMBL21385123 0.78 LPL (0.38) LIPGLPLEGFRPRMT5WDR77
SCHEMBL21382855 0.74 AHR (0.42) EGFRKDM4EMAPK1ATM
SCHEMBL23504623 0.74 LPL (0.47) LIPGLPLPRMT5WDR77KDM4E
SCHEMBL31062339 0.71 KDM4E (0.51) LIPGLPLEGFRPRMT5WDR77
SCHEMBL25908152 0.71 KDM4E (0.51) LIPGLPLEGFRPRMT5WDR77
SCHEMBL21764405 0.71 LPL (0.47) LIPGLPLPRMT5WDR77KDM4E
SCHEMBL21385121 0.70 MAPK1 (0.36) EGFRKDM4EMAPK1ATMKDR
SCHEMBL47074 0.70 LPL (0.53) LIPGLPLIRAK4CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019182360-A1 COMPOUND, ORGANIC LIGHT-EMITTING DEVICE AND DISPLAY DEVICE 에스케이머티리얼즈 주식회사 2019-09-26 WO disclosed