Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX1 | Q96LB2 | 3/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | CTPS1 | P17812 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SERPINH1 | P50454 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21384561 | 0.86 | ACLY (0.48) | MRGPRX1FFAR4SCN5ASCN9ACTPS1 | |
| SCHEMBL21381359 | 0.85 | MRGPRX1 (0.43) | MRGPRX1SLC6A3ABL1SCN5ASCN9A | |
| SCHEMBL21394567 | 0.84 | MRGPRX1 (0.44) | MRGPRX1SLC6A3ABL1CTPS1MAPT | |
| SCHEMBL2738023 | 0.83 | KDM4E (0.46) | FFAR4SLC6A3ABL1MAPTACLY | |
| SCHEMBL21384614 | 0.80 | MRGPRX1 (0.57) | MRGPRX1SLC6A3ABL1ACLY | |
| SCHEMBL11561114 | 0.77 | FFAR4 (0.40) | FFAR4SLC6A3ABL1MAPTACLY | |
| SCHEMBL2657833 | 0.74 | ABL1 (0.47) | SLC6A3ABL1MAPTMEN1LMNA | |
| SCHEMBL21384541 | 0.72 | ABL1 (0.48) | MRGPRX1SLC6A3ABL1MAPTACLY | |
| SCHEMBL17803504 | 0.71 | ABL1 (0.39) | MRGPRX1ABL1CTPS1ACLYMEN1 | |
| SCHEMBL21384566 | 0.71 | MRGPRX1 (0.42) | MRGPRX1SCN5ASCN9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019179436-A1 | ACID AMIDE COMPOUND AND USE THEREOF IN TREATMENT OF CANCERS | 成都海创药业有限公司 | 2019-09-26 | — | — | WO | disclosed |
| WO-2019179436-A1 | ACID AMIDE COMPOUND AND USE THEREOF IN TREATMENT OF CANCERS | 成都海创药业有限公司 | 2019-09-26 | — | — | WO | disclosed |