Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX1 | Q96LB2 | 5/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | CTPS1 | P17812 | 2/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TLR4 | O00206 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | TSPO | P30536 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21384579 | 0.84 | MRGPRX1 (0.41) | MRGPRX1SLC6A3MEN1KMT2AABL1 | |
| SCHEMBL21381359 | 0.83 | MRGPRX1 (0.43) | MRGPRX1SLC6A3ABL1ALDH1A1MAPT | |
| SCHEMBL21384614 | 0.77 | MRGPRX1 (0.57) | MRGPRX1SLC6A3ABL1TLR4TSPO | |
| SCHEMBL30810287 | 0.73 | KDM4E (0.45) | SLC6A3MEN1KMT2AABL1ALDH1A1 | |
| SCHEMBL30810266 | 0.71 | HPGD (0.50) | SLC6A3MEN1KMT2AABL1HCRTR1 | |
| SCHEMBL21384541 | 0.70 | ABL1 (0.48) | MRGPRX1SLC6A3MEN1KMT2AABL1 | |
| SCHEMBL21384561 | 0.70 | ACLY (0.48) | MRGPRX1CTPS1ALDH1A1KDM4E | |
| SCHEMBL10174510 | 0.70 | ABL1 (0.57) | SLC6A3MEN1KMT2AABL1HCRTR1 | |
| SCHEMBL10487662 | 0.70 | ABL1 (0.62) | SLC6A3MEN1KMT2AABL1HCRTR1 | |
| SCHEMBL21384566 | 0.69 | MRGPRX1 (0.42) | MRGPRX1ALDH1A1TSHRTLR4TSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019179436-A1 | ACID AMIDE COMPOUND AND USE THEREOF IN TREATMENT OF CANCERS | 成都海创药业有限公司 | 2019-09-26 | — | — | WO | disclosed |