Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.53 |
| ▸ | BCL9 | O00512 | 10/20 | 0.51 |
| ▸ | CTNNB1 | P35222 | 10/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.48 |
| ▸ | LIPE | Q05469 | 1/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30567993 | 1.00 | PDE4B (0.53) | PDE4BBCL9CTNNB1TP53MAPT | |
| SCHEMBL30567996 | 1.00 | PDE4B (0.53) | PDE4BBCL9CTNNB1TP53MAPT | |
| SCHEMBL23212068 | 1.00 | PDE4B (0.53) | PDE4BBCL9CTNNB1TP53MAPT | |
| SCHEMBL25864470 | 0.93 | GPR119 (0.52) | PDE4BBCL9CTNNB1TP53MAPT | |
| SCHEMBL29849889 | 0.91 | RORC (0.48) | PDE4BBCL9CTNNB1GPR119LIPE | |
| SCHEMBL20757253 | 0.91 | RORC (0.48) | PDE4BBCL9CTNNB1GPR119LIPE | |
| SCHEMBL23211941 | 0.86 | GPR119 (0.56) | PDE4BTP53MAPTGPR119LIPE | |
| SCHEMBL30272551 | 0.85 | LIPE (0.49) | BCL9CTNNB1GPR119LIPEUSP30 | |
| SCHEMBL30272555 | 0.85 | LIPE (0.49) | BCL9CTNNB1GPR119LIPEUSP30 | |
| SCHEMBL30910405 | 0.85 | LIPE (0.49) | BCL9CTNNB1GPR119LIPEUSP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3768684-A1 | OXAZINE MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2021-01-27 | — | — | EP | disclosed |
| WO-2019180185-A1 | OXAZINE MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2019-09-26 | — | — | WO | disclosed |