Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 8/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11443635 | 0.75 | FKBP1A (0.67) | FKBP1A | |
| SCHEMBL28351585 | 0.75 | FKBP1A (0.67) | FKBP1A | |
| SCHEMBL924014 | 0.75 | GABRA1 (0.53) | SIGMAR1FKBP1ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL10798191 | 0.75 | FKBP1A (0.49) | SIGMAR1FKBP1ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL25221210 | 0.74 | FABP7 (0.55) | FKBP1ASMN1; SMN2NPC1RAB9ATSHR | |
| Hydrochloric Acid SCHEMBL5474137 | 0.74 | FKBP1A (0.48) | SIGMAR1FKBP1ASMN1; SMN2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL30844756 | 0.74 | FKBP1A (0.48) | SIGMAR1FKBP1ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL8773327 | 0.73 | FKBP1A (0.58) | FKBP1ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL1706517 | 0.73 | FKBP1A (0.58) | FKBP1ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL2679494 | 0.73 | FKBP1A (0.58) | FKBP1ASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019179515-A1 | RECEPTOR INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 北京泰德制药股份有限公司 | 2019-09-26 | — | — | WO | disclosed |