SCHEMBL1706517

SCHEMBL1706517

O=C(OCc1ccccc1)C1CCCN1O

nearest known ligand 0.58

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 11/20 0.58
PREP P48147 3/20 0.49
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2679494 1.00 FKBP1A (0.58) FKBP1APREPNPC1RAB9ASMN1; SMN2
SCHEMBL8773327 1.00 FKBP1A (0.58) FKBP1APREPNPC1RAB9ASMN1; SMN2
Hydrochloric Acid SCHEMBL1784260 0.99 FKBP1A (0.57) FKBP1APREPNPC1RAB9ASMN1; SMN2
Hydrochloric Acid SCHEMBL9251636 0.99 FKBP1A (0.57) FKBP1APREPNPC1RAB9ASMN1; SMN2
SCHEMBL28351585 0.84 FKBP1A (0.67) FKBP1APREP
SCHEMBL13148433 0.84 FKBP1A (0.57) FKBP1APREPSMN1; SMN2
SCHEMBL13413549 0.84 FKBP1A (0.57) FKBP1APREPSMN1; SMN2
SCHEMBL13099455 0.84 FKBP1A (0.60) FKBP1APREP
SCHEMBL27553714 0.84 FKBP1A (0.57) FKBP1APREPNPC1RAB9ASMN1; SMN2
SCHEMBL12869918 0.84 FKBP1A (0.60) FKBP1APREP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8486370-B2 Heterocyclic ligands for integrin imaging and therapy THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2013-07-16 US claimed
US-20100310455-A1 Heterocyclic Ligands for Integrin Imaging and Therapy THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-12-09 US claimed
US-7576175-B2 Amino acid terminated diphenylurea derivatives; display high binding affinity, specificity, and stability; use in treating cancer, inflammatory diseases, and autoimmune diseases THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-08-18 US claimed
WO-2008031016-A2 HETEROCYCLIC LIGANDS FOR INTEGRIN IMAGING AND THERAPY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-03-13 WO claimed
WO-2005122379-A9 ALPHA-4 BETA-1 INTEGRIN LIGANDS FOR IMAGING AND THERAPY UNIV CALIFORNIA (US) 2006-03-09 WO claimed
US-20060019900-A1 Alpha-4 beta-1 integrin ligands for imaging and therapy THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-01-26 US claimed
WO-2005122379-A2 ALPHA-4 BETA-1 INTEGRIN LIGANDS FOR IMAGING AND THERAPY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-12-22 WO claimed
WO-2026105061-A1 ANTIBODY-DRUG CONJUGATES THAT BIND CDCP1 AND USES THEREOF PHEON THERAPEUTICS LTD (GB) 2026-05-21 WO disclosed
WO-2026090584-A2 METHODS OF TREATING PERIPHERAL NERVOUS SYSTEM MYELINATION CONDITIONS Artery Therapeutics, Inc. (US) 2026-04-30 WO disclosed
EP-4731270-A1 COMBINATION THERAPY WITH PEPTIDE RECEPTOR RADIONUCLIDE AND DNA REPAIR INHIBITOR The Regents of The University of California (US) 2026-04-29 EP disclosed
US-20260083852-A1 PROTEOGLYCAN MIMETICS FOR ENHANCED WOUND HEALING, ANGIOGENESIS, AND VASCULAR REPAIR UNIV CALIFORNIA (US) 2026-03-26 US disclosed
US-12485182-B2 Proteoglycan mimetics for enhanced wound healing, angiogenesis, and vascular repair THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-12-02 US disclosed
EP-4633738-A1 CYTOTOXIC COMPOUNDS Pheon Therapeutics Ltd (GB) 2025-10-22 EP disclosed
US-20030153785-A1 Method for preserving quaternary ammonium salt TOKUYAMA CORPORATION (JP) 2003-08-14 US disclosed
US-6458948-B1 MIXING A QUATERNARY AMMONIUM SALT HAVING A PARTICULAR TRIAZINE RING IN THE MOLECULES THEREOF, A CARBOXYLIC ACID COMPOUND AND A COMPOUND HAVING A NUCLEOPHILIC FUNCTIONAL GROUP, TO CONDENSE THE CARBOXYLIC ACID WITH THE COMPOUND HAVING THE NUCLEOPHILIC TOKUYAMA CORPORATION (JP) 2002-10-01 US disclosed
EP-1178043-A1 METHOD FOR STORING QUATERNARY AMMONIUM SALT TOKUYAMA CORPORATION (JP) 2002-02-06 EP disclosed
EP-1085000-A1 PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE AND CONDENSING AGENT COMPRISING QUATERNARY AMMONIUM SALT TOKUYAMA CORPORATION (JP) 2001-03-21 EP disclosed
US-5965556-A KETO-ACID AMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND METHODS FOR INHIBITING THE ACTIVITY OF SERINE PROTEASE OR THIOL PROTEASE BY ADMINISTERING THE DERIVATIVE TO A MAMMAL; ALZHEIMER'S DISEASE ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYUKAI (JP) 1999-10-12 US disclosed
US-5756763-A ENZYME INHIBITOR ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYUKAI (JP) 1998-05-26 US disclosed
EP-0709373-A1 NOVEL PYRROLIDINE DERIVATIVE ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1996-05-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100310455-A1 Heterocyclic Ligands for Integrin Imaging and Therapy ITGA1, ITGAL, ITGA4 FKBP1A 3885/4885PREP 2276/4885NPC1 3565/4885
US-20060019900-A1 Alpha-4 beta-1 integrin ligands for imaging and therapy ITGA4, ITGB4, ITGA1 FKBP1A 3776/4885PREP 2443/4885NPC1 2481/4885
US-20030153785-A1 Method for preserving quaternary ammonium salt NHERF1, ASH1L, ATP6V1B1 FKBP1A 1410/4885PREP 1471/4885NPC1 1782/4885
US-12485182-B2 Proteoglycan mimetics for enhanced wound healing, angiogenesis, and vascular repair PDGFA, PDGFRB, TEK FKBP1A 1555/4885PREP 380/4885NPC1 4205/4885
US-20260083852-A1 PROTEOGLYCAN MIMETICS FOR ENHANCED WOUND HEALING, ANGIOGENESIS, AND VASCULAR REPAIR PDGFA, DCLRE1A, PDGFRA FKBP1A 2340/4885PREP 324/4885NPC1 3927/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.