Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.41 |
| ▸ | PPARG | P37231 | 6/20 | 0.41 |
| ▸ | PPARD | Q03181 | 6/20 | 0.41 |
| ▸ | PPARA | Q07869 | 6/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL680659 | 0.98 | CYP4F2 (0.41) | CYP4F2CYP4A11AKR1B1CES2GPR84 | |
| SCHEMBL2141772 | 0.98 | CES2 (0.45) | CES2GPR84PPARGPPARDPPARA | |
| SCHEMBL8919538 | 0.98 | CYP4F2 (0.41) | CYP4F2CYP4A11AKR1B1CES2GPR84 | |
| SCHEMBL5049746 | 0.98 | CES2 (0.45) | CES2GPR84PPARGPPARDPPARA | |
| SCHEMBL5046725 | 0.98 | CES2 (0.45) | CES2GPR84PPARGPPARDPPARA | |
| SCHEMBL20915260 | 0.98 | CES2 (0.45) | CES2GPR84PPARGPPARDPPARA | |
| SCHEMBL20936507 | 0.98 | CES2 (0.45) | CES2GPR84PPARGPPARDPPARA | |
| SCHEMBL20915383 | 0.98 | CES2 (0.45) | CES2GPR84PPARGPPARDPPARA | |
| SCHEMBL20936490 | 0.98 | CES2 (0.45) | CES2GPR84PPARGPPARDPPARA | |
| SCHEMBL313593 | 0.98 | CES2 (0.45) | CES2GPR84PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2504099-B1 | HYDROPROCESSING BULK CATALYST, IT'S USE AND METHODS OF MAKING THEREOF | CHEVRON USA INC (US) | 2021-08-11 | — | — | EP | claimed |
| EP-1722741-B1 | DENTAL MATERIAL BASED ON ALKOXYSILYL-FUNCTIONAL POLYETHERS | KETTENBACH GMBH & CO KG (DE) | 2009-04-01 | — | — | EP | claimed |
| US-20070173557-A1 | Dental material based on alkoxysilyl-functional polyethers containing a salt of a strong base as catalyst | KETTENBACH GMBH & CO. KG (DE) | 2007-07-26 | — | — | US | claimed |
| EP-1722741-A1 | DENTAL MATERIAL BASED ON ALKOXYSILYL-FUNCTIONAL POLYETHERS | Kettenbach GmbH & CO. KG (DE) | 2006-11-22 | — | — | EP | claimed |
| WO-2005077321-A1 | DENTAL MATERIAL BASED ON ALKOXYSILYL-FUNCTIONAL POLYETHERS | KETTENBACH GMBH & CO. KG (DE) | 2005-08-25 | — | — | WO | claimed |
| US-20180177760-A1 | COMPOSITIONS COMPRISING BIOREVERSIBLE DERIVATIVES OF HYDROXY N-SUBSTITUTED-2-AMINOTETRALINS, AND RELATED DOSAGE FORMS | SPRIASO LLC (US) | 2018-06-28 | — | — | US | disclosed |
| US-9956201-B2 | Compositions comprising bioreversible derivatives of hydroxy N-substituted-2-aminotetralins, and related dosage forms | SPRIASO LLC (US) | 2018-05-01 | — | — | US | disclosed |
| US-20160015684-A1 | COMPOSITIONS COMPRISING BIOREVERSIBLE DERIVATIVES OF HYDROXY N- SUBSTITUTED-2-AMINOTETRALINS, DOSAGE FORMS, AND RELATED METHODS | SPRIASO LLC | 2016-01-21 | — | — | US | disclosed |
| US-20160016887-A1 | Methods of treating a subject using bioreversible derivatives of hydroxy n-substituted-2-aminotetralins | SPRIASO LLC | 2016-01-21 | — | — | US | disclosed |
| EP-1738737-B1 | Dimensionally stable articles from cured condensation-crosslinked dental material | KETTENBACH GMBH & CO KG (DE) | 2012-05-16 | — | — | EP | disclosed |
| US-7902269-B2 | Dental material based on alkoxysilyl-functional polyethers containing a salt of a strong base as catalyst | KETTENBACH GMBH & CO. KG (DE) | 2011-03-08 | — | — | US | disclosed |
| US-7790781-B2 | Condensation-crosslinkable dental material hardening to dimensionally stable casts | KETTENBACH GMBH & CO. KG (DE) | 2010-09-07 | — | — | US | disclosed |
| CN-1230536-A | Process for producing lanthanide metal carboxylate | QIMEI IND CO LTD (CN) | 1999-10-06 | — | — | CN | disclosed |
| EP-0512346-B1 | Process for preparing metal carboxylates and their use in the polymerisation of monomers suitable for the Ziegler-Natta polymerisation | BAYER AG (DE) | 1995-06-28 | — | — | EP | disclosed |
| US-5220045-A | PROCESS FOR THE PRODUCTION OF METAL CARBOXYLATES AND THEIR USE FOR THE POLYMERIZATION OF MONOMERS SUITABLE FOR ZIEGLER-NATTA POLYMERIZATION | BAYER AKTIENGESELLSCHAFT (DE) | 1993-06-15 | — | — | US | disclosed |
| EP-0512346-A2 | Process for preparing metal carboxylates and their use in the polymerisation of monomers suitable for the Ziegler-Natta polymerisation | BAYER AG (DE) | 1992-11-11 | — | — | EP | disclosed |
| EP-0011184-B2 | CATALYST, ITS MANUFACTURE AND ITS USE IN THE SOLUTION-POLYMERISATION OF CONJUGATED DIENES | BAYER AG (DE) | 1988-05-18 | — | — | EP | disclosed |
| EP-0011184-B1 | CATALYST, ITS MANUFACTURE AND ITS USE IN THE SOLUTION-POLYMERISATION OF CONJUGATED DIENES | BAYER AG (DE) | 1983-05-11 | — | — | EP | disclosed |
| EP-0011184-A1 | Catalyst, its manufacture and its use in the solution-polymerisation of conjugated dienes | BAYER AG (DE) | 1980-05-28 | — | — | EP | disclosed |
| US-4104141-A | Electrochemical oxidation of alkoxy-substituted aromatic compounds | UOP INC. (US) | 1978-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070173557-A1 | Dental material based on alkoxysilyl-functional polyethers containing a salt of a strong base as catalyst | CSNK1A1L, TBL3, DCLK3 | CYP4F2 4665/4885CYP4A11 4397/4885AKR1B1 3278/4885 |
| US-20160016887-A1 | Methods of treating a subject using bioreversible derivatives of hydroxy n-substituted-2-aminotetralins | SLC7A1, CYP2D6, SLC19A1 | CYP4F2 84/4885CYP4A11 125/4885AKR1B1 386/4885 |
| US-20160015684-A1 | COMPOSITIONS COMPRISING BIOREVERSIBLE DERIVATIVES OF HYDROXY N- SUBSTITUTED-2-AMINOTETRALINS, DOSAGE FORMS, AND RELATED METHODS | SLC7A1, CYP2D6, CYP3A7 | CYP4F2 24/4885CYP4A11 58/4885AKR1B1 413/4885 |
| US-20180177760-A1 | COMPOSITIONS COMPRISING BIOREVERSIBLE DERIVATIVES OF HYDROXY N-SUBSTITUTED-2-AMINOTETRALINS, AND RELATED DOSAGE FORMS | SLC7A1, CYP2D6, CYP3A7 | CYP4F2 32/4885CYP4A11 70/4885AKR1B1 423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.