SCHEMBL21385274

SCHEMBL21385274

Brc1ccc2c(c1)Sc1cccc3ccnc-2c13

nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.43
TYMS P04818 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP2C19 P33261 1/20 0.35
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25482003 0.81 MAOA (0.50) MAOATYMS
SCHEMBL17283586 0.79 TYMS (0.50) TYMS
SCHEMBL31301093 0.79 TYMS (0.50) TYMS
SCHEMBL21382715 0.77 MAOA (0.37) MAOATYMSCYP1A2CYP2C19HTT
SCHEMBL21383216 0.71 AHR (0.41) MAOATYMSCYP1A2CYP2C19HTT
SCHEMBL17283583 0.69 TYMS (0.50) TYMSCYP1A2
SCHEMBL30496684 0.69 TYMS (0.50) TYMSCYP1A2
SCHEMBL21385069 0.69 MAOA (0.37) MAOATYMSCYP1A2CYP2C19HTT
SCHEMBL17283766 0.68 TYMS (0.45) MAOATYMS
SCHEMBL25776611 0.68 MAOA (0.43) MAOATYMSCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019182360-A1 COMPOUND, ORGANIC LIGHT-EMITTING DEVICE AND DISPLAY DEVICE 에스케이머티리얼즈 주식회사 2019-09-26 WO disclosed