SCHEMBL21383216

SCHEMBL21383216

Brc1ccc2c(c1)Oc1cccc3ccnc-2c13

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
AHR P35869 3/20 0.41
MAOA P21397 1/20 0.40
KDM4E B2RXH2 1/20 0.39
MAPK1 P28482 1/20 0.39
ATM Q13315 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2C19 P33261 1/20 0.38
HTT P42858 1/20 0.38
TYMS P04818 1/20 0.36
PTGES O14684 1/20 0.35
EGFR P00533 1/20 0.32
PLAU P00749 2/20 0.32
PLG P00747 1/20 0.32
PLAT P00750 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21383190 0.89 MAOA (0.37) AHRMAOAKDM4EMAPK1ATM
SCHEMBL25481886 0.81 MAOA (0.46) MAOAKDM4EMAPK1ATMTYMS
SCHEMBL17283689 0.79 MAPK1 (0.65) AHRKDM4EMAPK1ATMCYP1A2
SCHEMBL30005857 0.79 MAPK1 (0.65) AHRKDM4EMAPK1ATMCYP1A2
SCHEMBL21385123 0.75 LPL (0.38) MAOAKDM4EMAPK1ATMTYMS
SCHEMBL24277782 0.73 AHR (0.70) AHRKDM4EMAPK1ATMCYP1A2
SCHEMBL21382855 0.72 AHR (0.42) AHRKDM4EMAPK1ATMCYP1A2
SCHEMBL19665992 0.72 KDM4E (0.44) AHRKDM4EMAPK1ATMCYP1A2
SCHEMBL21385099 0.71 LIPG (0.48) MAOAKDM4EMAPK1ATMEGFR
SCHEMBL21385274 0.71 MAOA (0.43) MAOACYP1A2CYP2C19HTTTYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019182360-A1 COMPOUND, ORGANIC LIGHT-EMITTING DEVICE AND DISPLAY DEVICE 에스케이머티리얼즈 주식회사 2019-09-26 WO disclosed