Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | PRKDC | P78527 | 2/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | LPL | P06858 | 5/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.37 |
| ▸ | LGMN | Q99538 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19991500 | 0.90 | ALDH1A1 (0.54) | ALDH1A1PRKDCPIK3CDPIK3CAPIK3CB | |
| SCHEMBL4475253 | 0.88 | ALDH1A1 (0.41) | ALDH1A1ALDH1A3SMN1; SMN2IDO1TDO2 | |
| SCHEMBL29266604 | 0.80 | LPL (0.42) | ALDH1A1LMNASMN1; SMN2IDO1TDO2 | |
| SCHEMBL790296 | 0.79 | ALDH1A1 (0.43) | ALDH1A1PRKDCALDH3A1ALDH1A3LMNA | |
| SCHEMBL13717675 | 0.79 | MAPT (0.51) | ALDH1A1ALDH3A1ALDH1A3LMNAMEN1 | |
| SCHEMBL25259314 | 0.79 | SMN1; SMN2 (0.45) | ALDH1A1PRKDCLMNASMN1; SMN2MAPT | |
| SCHEMBL23926530 | 0.78 | MAPT (0.54) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL32933328 | 0.78 | MAPT (0.54) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13718438 | 0.77 | ALDH1A1 (0.46) | ALDH1A1LMNAKMT2ASMN1; SMN2IDO1 | |
| SCHEMBL29508091 | 0.77 | ALDH1A1 (0.46) | ALDH1A1LMNAKMT2ASMN1; SMN2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3768675-A1 | NOVEL TRIAZOLONE DERIVATIVES OR SALTS THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | Yuhan Corporation (KR) | 2021-01-27 | — | — | EP | disclosed |
| WO-2019180646-A1 | NOVEL TRIAZOLONE DERIVATIVES OR SALTS THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | YUHAN CORPORATION (KR) | 2019-09-26 | — | — | WO | disclosed |