Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 2/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | LGMN | Q99538 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29508091 | 0.89 | ALDH1A1 (0.46) | LPLLIPGALDH1A1ROCK1HPGD | |
| SCHEMBL13718438 | 0.89 | ALDH1A1 (0.46) | LPLLIPGALDH1A1ROCK1HPGD | |
| SCHEMBL14243487 | 0.89 | LPL (0.44) | LPLLIPGALDH1A1ROCK1HPGD | |
| SCHEMBL30988471 | 0.89 | LPL (0.44) | LPLLIPGALDH1A1ROCK1HPGD | |
| SCHEMBL27250550 | 0.83 | LPL (0.39) | LPLLIPGROCK1IDO1TDO2 | |
| SCHEMBL30925336 | 0.83 | LPL (0.39) | LPLLIPGROCK1IDO1TDO2 | |
| SCHEMBL790296 | 0.82 | ALDH1A1 (0.43) | LPLLIPGALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL13717675 | 0.82 | MAPT (0.51) | ALDH1A1HPGDSMN1; SMN2LMNANPC1 | |
| SCHEMBL17102336 | 0.80 | NOTUM (0.46) | ALDH1A1SMN1; SMN2LMNAKDM4EMAPT | |
| SCHEMBL21385308 | 0.80 | ALDH1A1 (0.45) | LPLLIPGALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290386-A | 7-Hydroxyflavone compound, and preparation method and application thereof | 国科大杭州高等研究院 | 2024-07-05 | — | — | CN | disclosed |