SCHEMBL21385366

SCHEMBL21385366

C=CC(=C)CCC(=O)C=C

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.43
ALDH1A1 P00352 4/20 0.43
LMNA P02545 1/20 0.33
FGFR4 P22455 1/20 0.32
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
BLM P54132 1/20 0.30
SLC6A3 Q01959 1/20 0.30
MEN1 O00255 1/20 0.30
CYP2D6 P10635 1/20 0.30
NFKB1 P19838 1/20 0.30
CYP2C19 P33261 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3629050 0.85 TSHR (0.56) TSHRALDH1A1LMNAFGFR4ALOX15
SCHEMBL19942090 0.82 TSHR (0.39) TSHRALDH1A1LMNANFKB1
SCHEMBL27940802 0.82 TSHR (0.52) TSHRALDH1A1
SCHEMBL11782752 0.78
SCHEMBL2309685 0.74
SCHEMBL21093424 0.74 THRA (0.37) TSHRALDH1A1
SCHEMBL17315005 0.74 ALOX15 (0.48) TSHRALDH1A1LMNAALOX15HSD17B10
SCHEMBL1988202 0.73 ALDH1A1 (0.50) TSHRALDH1A1LMNAFGFR4MAPK1
SCHEMBL6557587 0.73 ALDH1A1 (0.50) TSHRALDH1A1LMNAFGFR4MAPK1
SCHEMBL28371728 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10421857-B2 Photocurable composition and patterned body manufactured by using the composition SAMSUNG DISPLAY CO., LTD. (KR) 2019-09-24 US disclosed