Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16492254 | 0.97 | TRPC5 (0.41) | TRPC5ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL29429566 | 0.94 | TRPC5 (0.39) | TRPC5ALDH1A1KMT2AMEN1TP53 | |
| SCHEMBL540713 | 0.94 | TRPC5 (0.39) | TRPC5ALDH1A1KMT2AMEN1TP53 | |
| SCHEMBL14027738 | 0.93 | TRPC5 (0.41) | TRPC5ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL14271799 | 0.91 | LMNA (0.41) | TRPC5ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL21073879 | 0.89 | TRPC5 (0.45) | TRPC5ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL14007669 | 0.87 | TRPC5 (0.37) | TRPC5ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL6369495 | 0.86 | TRPC5 (0.40) | TRPC5ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL14027737 | 0.86 | TRPC5 (0.36) | TRPC5ALDH1A1KMT2AMEN1TP53 | |
| SCHEMBL4855775 | 0.86 | TRPC5 (0.39) | TRPC5ALDH1A1KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10420788-B2 | — | — | 2019-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10420788-B2 | — | PNP, ADAR, NT5C2 | TRPC5 3222/4885ALDH1A1 3086/4885KMT2A 3420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.