Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 7/20 | 0.55 |
| ▸ | TK1 | P04183 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PNP | P00491 | 6/20 | 0.45 |
| ▸ | XDH | P47989 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | VCP | P55072 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | EDNRA | P25101 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HBB | P68871 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24317687 | 0.95 | HPRT1 (0.53) | HPRT1TK1MEN1KMT2APNP | |
| SCHEMBL18479143 | 0.93 | HPRT1 (0.55) | HPRT1TK1MEN1KMT2APNP | |
| SCHEMBL18474881 | 0.93 | HPRT1 (0.55) | HPRT1TK1MEN1KMT2APNP | |
| SCHEMBL22759884 | 0.93 | HPRT1 (0.55) | HPRT1TK1MEN1KMT2APNP | |
| SCHEMBL18476745 | 0.93 | HPRT1 (0.55) | HPRT1TK1MEN1KMT2APNP | |
| SCHEMBL22380975 | 0.93 | HPRT1 (0.55) | HPRT1TK1MEN1KMT2APNP | |
| SCHEMBL21516014 | 0.90 | HPRT1 (0.57) | HPRT1TK1MEN1KMT2APNP | |
| SCHEMBL21943253 | 0.88 | HPRT1 (0.53) | HPRT1TK1MEN1KMT2APNP | |
| SCHEMBL21127905 | 0.86 | HPRT1 (0.50) | HPRT1TK1MEN1KMT2APNP | |
| SCHEMBL21311340 | 0.84 | HPRT1 (0.61) | HPRT1TK1MEN1KMT2APNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11642364-B2 | Exon skipping oligomer conjugates for muscular dystrophy | SAREPTA THERAPEUTICS, INC. (US) | 2023-05-09 | — | — | US | disclosed |
| US-10464965-B2 | Substituted nucleosides, nucleotides and analogs thereof | ALIOS BIOPHARMA, INC. (US) | 2019-11-05 | — | — | US | disclosed |
| US-10421771-B2 | — | — | 2019-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10464965-B2 | Substituted nucleosides, nucleotides and analogs thereof | PNP, NT5C3B, ADAR | HPRT1 19/4885TK1 150/4885MEN1 3489/4885 |
| US-11642364-B2 | Exon skipping oligomer conjugates for muscular dystrophy | UTRN, SMN1; SMN2, DCLRE1B | HPRT1 3673/4885TK1 1729/4885MEN1 4304/4885 |
| US-10421771-B2 | — | PNP, ADAR, NT5C2 | HPRT1 21/4885TK1 223/4885MEN1 4128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.