SCHEMBL2138598

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30316128	0.80	NFKB1 (1.00)	NFKB1NFKB2RELAABL1ALDH1A1
	SCHEMBL2139370	0.80	NFKB1 (1.00)	NFKB1NFKB2RELAABL1ALDH1A1
	SCHEMBL2142554	0.80	NFKB1 (0.66)	NFKB1NFKB2RELASMN1; SMN2ABL1
	SCHEMBL27735776	0.80	NFKB1 (0.70)	NFKB1NFKB2RELASMN1; SMN2ABL1
	SCHEMBL14046922	0.79	NFKB1 (0.71)	NFKB1NFKB2RELAABL1ALDH1A1
	SCHEMBL2139666	0.78	NFKB1 (0.69)	NFKB1NFKB2RELAABL1ALDH1A1
	SCHEMBL2141296	0.77	NFKB1 (0.72)	NFKB1NFKB2RELAABL1ALDH1A1
	SCHEMBL2139185	0.77	NFKB1 (0.66)	NFKB1NFKB2RELAABL1ALDH1A1
	SCHEMBL2137790	0.77	NFKB1 (0.78)	NFKB1NFKB2RELAABL1ALDH1A1
	SCHEMBL2136321	0.74	NFKB1 (0.89)	NFKB1NFKB2RELASMN1; SMN2ABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.