Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 8/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.50 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19825999 | 0.83 | SMN1; SMN2 (0.46) | RAB9ANPC1SMN1; SMN2KMT2APOLB | |
| SCHEMBL17244567 | 0.81 | SMYD3 (0.45) | — | |
| SCHEMBL13802232 | 0.80 | RXFP1 (0.59) | SRCRAB9ANPC1SMN1; SMN2HDAC3 | |
| SCHEMBL155297 | 0.78 | RAB9A (0.64) | SRCRAB9ANPC1SMN1; SMN2HDAC3 | |
| SCHEMBL10668382 | 0.78 | SRC (0.52) | SRCRAB9AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL10092552 | 0.78 | RAB9A (0.58) | SRCRAB9AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL13536799 | 0.78 | GAA (0.46) | SMN1; SMN2KMT2APOLBALDH1A1MEN1 | |
| SCHEMBL19889897 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL2303356 | 0.77 | SRC (0.59) | SRCRAB9ANPC1SMN1; SMN2HDAC3 | |
| SCHEMBL22839761 | 0.76 | TSHR (0.45) | SMN1; SMN2KMT2APOLBALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3904450-A1 | COMPOSITION AND MOLDED ARTICLE | Akita University (JP) | 2021-11-03 | — | — | EP | disclosed |
| WO-2020247872-A1 | T-CELL DEPLETING THERAPIES | Magenta Therapeutics, Inc. (US) | 2020-12-10 | — | — | WO | disclosed |
| WO-2020113188-A2 | METHODS FOR DOSING AND TREATMENT OF B CELL MALIGNANCIES IN ADOPTIVE CELL THERAPY | JUNO THERAPEUTICS, INC. (US) | 2020-06-04 | — | — | WO | disclosed |
| EP-2739139-B1 | AGONISTS OF SRC HOMOLOGY-2 CONTAINING PROTEIN TYROSINE PHOSPHATASE-1 AND TREATMENT METHODS USING THE SAME | UNIV NAT TAIWAN (TW) | 2019-09-25 | — | — | EP | disclosed |