Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 8/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.50 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155127 | 0.84 | SRC (0.53) | SRCRAB9AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL10668375 | 0.83 | TSHR (0.38) | SRCRAB9AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL3772999 | 0.81 | GRIN2D (0.58) | SRCRAB9AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL14445095 | 0.81 | TSHR (0.37) | SRCRAB9AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL10788753 | 0.81 | SRC (0.50) | SRCRAB9AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL7877522 | 0.81 | LOXL2 (0.47) | PLGPLAUPLATKLKB1PRSS1 | |
| SCHEMBL14542726 | 0.79 | SRC (0.49) | SRCRAB9AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL21386360 | 0.78 | SRC (0.52) | SRCRAB9AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL10092552 | 0.78 | RAB9A (0.58) | SRCRAB9AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL155297 | 0.78 | RAB9A (0.64) | SRCRAB9ANPC1SMN1; SMN2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4743687-A | HYPOTENSIVE AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1988-05-10 | — | — | US | disclosed |