Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.67 |
| ▸ | EGFR | P00533 | 2/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | TEC | P42680 | 1/20 | 0.48 |
| ▸ | BMX | P51813 | 1/20 | 0.48 |
| ▸ | CD69 | Q07108 | 1/20 | 0.48 |
| ▸ | ITK | Q08881 | 1/20 | 0.48 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.48 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.48 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21386777 | 0.95 | BTK (0.75) | BTKEGFR | |
| SCHEMBL17816357 | 0.91 | BTK (0.77) | BTKEGFRKCNH2TECBMX | |
| SCHEMBL21386770 | 0.88 | BTK (0.66) | BTKEGFRITK | |
| SCHEMBL21386780 | 0.88 | BTK (0.66) | BTKEGFRITK | |
| SCHEMBL21386692 | 0.88 | BTK (0.54) | BTKEGFRTECBMXITK | |
| SCHEMBL21386739 | 0.87 | BTK (0.54) | BTKEGFRITK | |
| SCHEMBL21386733 | 0.87 | BTK (0.62) | BTKEGFRKCNH2ITK | |
| SCHEMBL18877721 | 0.86 | BTK (0.86) | BTKEGFRKCNH2TECBMX | |
| SCHEMBL14228143 | 0.86 | BTK (0.86) | BTKEGFRKCNH2TECBMX | |
| SCHEMBL21386748 | 0.86 | BTK (0.74) | BTKEGFRKCNH2TECBMX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3543239-A1 | SELECTIVE BRUTON'S TYROSINE KINASE INHIBITOR AND USE THEREOF | Hangzhou Hertz Pharmaceutical Co., Ltd. (CN) | 2019-09-25 | — | — | EP | disclosed |