SCHEMBL21387785 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	BIRC2	Q13490	4/20	0.46

▸	MMP3	P08254	11/20	0.38

▸	MMP1	P03956	9/20	0.37

▸	MMP2	P08253	8/20	0.37

▸	MMP7	P09237	3/20	0.37

▸	MMP9	P14780	3/20	0.37

▸	DPP4	P27487	1/20	0.35

▸	DPP8	Q6V1X1	1/20	0.35

▸	DPP9	Q86TI2	1/20	0.35

▸	MMP14	P50281	1/20	0.34

▸	PDF	Q9HBH1	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL21387112	0.92	BIRC2 (0.47)	BIRC2MMP3MMP1MMP2MMP7
Actinonin SCHEMBL14490676	0.84	BIRC2 (0.56)	BIRC2MMP3MMP1MMP2MMP7
Actinonin SCHEMBL123273	0.84	BIRC2 (0.56)	BIRC2MMP3MMP1MMP2MMP7
Actinonin SCHEMBL279450	0.84	BIRC2 (0.56)	BIRC2MMP3MMP1MMP2MMP7
Actinonin SCHEMBL12601775	0.84	BIRC2 (0.56)	BIRC2MMP3MMP1MMP2MMP7
Actinonin SCHEMBL279122	0.84	BIRC2 (0.56)	BIRC2MMP3MMP1MMP2MMP7
SCHEMBL6294118	0.81	BIRC2 (0.55)	BIRC2MMP3MMP1MMP2MMP7
SCHEMBL18328823	0.79	MMP3 (0.49)	BIRC2MMP3MMP1MMP2MMP7
SCHEMBL8979692	0.78	REN (0.56)	BIRC2MMP3MMP1MMP2MMP7
SCHEMBL6297375	0.78	REN (0.56)	BIRC2MMP3MMP1MMP2MMP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-3542824-A1	Ras PROTEIN DEGRADATION INDUCING MOLECULE AND PHARMACEUTICAL COMPOSITION	Tokyo University of Science Foundation (JP)	2019-09-25	—	—	EP	disclosed