Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 20/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21387504 | 0.95 | KIT (0.80) | KIT | |
| SCHEMBL21387398 | 0.92 | KIT (0.82) | KIT | |
| SCHEMBL14739173 | 0.92 | KIT (1.00) | KIT | |
| SCHEMBL21387471 | 0.91 | KIT (0.89) | KIT | |
| SCHEMBL20844809 | 0.91 | KIT (0.93) | KIT | |
| SCHEMBL14738588 | 0.90 | KIT (1.00) | KIT | |
| SCHEMBL14738218 | 0.90 | KIT (1.00) | KIT | |
| SCHEMBL14740017 | 0.90 | KIT (0.86) | KIT | |
| SCHEMBL21372452 | 0.90 | KIT (0.86) | KIT | |
| SCHEMBL14740096 | 0.89 | KIT (0.85) | KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2751104-B1 | COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS | NOVARTIS AG (CH) | 2019-09-25 | — | — | EP | disclosed |