Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.38 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KRAS | P01116 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20177319 | 0.72 | EGLN1 (0.55) | EGLN1POLBMEN1KMT2ALMNA | |
| SCHEMBL978528 | 0.68 | HPGD (0.53) | POLBMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL5841965 | 0.67 | MRGPRX4 (0.54) | EGLN1POLBMEN1KMT2ALMNA | |
| SCHEMBL24460040 | 0.66 | GAA (0.51) | POLBMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6321530 | 0.66 | MRGPRX4 (0.49) | TAS1R3TAS1R1POLBMEN1KMT2A | |
| SCHEMBL15337724 | 0.65 | EGLN1 (0.48) | EGLN1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL11125709 | 0.65 | STAT3 (0.49) | POLBMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL10751701 | 0.64 | LMNA (0.55) | POLBMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL20752304 | 0.63 | MAPT (0.38) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL24459955 | 0.63 | KRAS (0.61) | POLBMEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3542824-A1 | Ras PROTEIN DEGRADATION INDUCING MOLECULE AND PHARMACEUTICAL COMPOSITION | Tokyo University of Science Foundation (JP) | 2019-09-25 | — | — | EP | disclosed |