Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | DGKA | P23743 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19100033 | 0.84 | GAA (0.44) | ALDH1A1LMNAHSD17B10 | |
| Hydrochloric Acid SCHEMBL7657380 | 0.82 | GAA (0.43) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL27017171 | 0.80 | ALDH1A1 (0.38) | NAAADGKAALDH1A1HCAR2MAPT | |
| SCHEMBL6437102 | 0.78 | NAAA (0.38) | NAAADGKAALDH1A1HCAR2MAPT | |
| SCHEMBL6431290 | 0.76 | MAPT (0.37) | NAAADGKAALDH1A1HCAR2MAPT | |
| SCHEMBL6431283 | 0.76 | MAPT (0.37) | NAAADGKAALDH1A1HCAR2MAPT | |
| Hydrochloric Acid SCHEMBL28313226 | 0.76 | L3MBTL1 (0.37) | NAAADGKAALDH1A1HCAR2MAPT | |
| SCHEMBL17504497 | 0.75 | TSHR (0.40) | ALDH1A1MAPTLMNAHSD17B10 | |
| SCHEMBL9744364 | 0.75 | — | — | |
| SCHEMBL14685074 | 0.75 | TSHR (0.40) | ALDH1A1MAPTLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3147284-B1 | INHIBITORS OF INFLUENZA VIRUSES REPLICATION | VERTEX PHARMA (US) | 2019-09-25 | — | — | EP | disclosed |