SCHEMBL21389133

SCHEMBL21389133

CC1(C)CCN(CCNC(=O)CSCC(=O)O)C1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FABP4 P15090 3/20 0.39
▸ FABP3 P05413 2/20 0.39
▸ GAA P10253 1/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.36
▸ ALDH1A1 P00352 2/20 0.35
▸ ATM Q13315 1/20 0.33
▸ MAPK1 P28482 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ USP2 O75604 1/20 0.33
▸ OPRM1 P35372 1/20 0.32
▸ OPRD1 P41143 1/20 0.32
▸ LMNA P02545 1/20 0.32
▸ CYP2D6 P10635 1/20 0.32
▸ HIF1A Q16665 1/20 0.32
▸ TP53 P04637 1/20 0.32
▸ PER2 O15055 1/20 0.31
▸ CRY2 Q49AN0 1/20 0.31
▸ POLB P06746 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24796267 0.92 FABP3 (0.43) FABP4FABP3GAAL3MBTL1ALDH1A1
SCHEMBL26746216 0.90 KMT2A (0.38) FABP4FABP3L3MBTL1ALDH1A1ATM
SCHEMBL21389424 0.86 KMT2A (0.31) KMT2A
SCHEMBL24795920 0.85 L3MBTL1 (0.40) GAAL3MBTL1ALDH1A1KMT2ALMNA
SCHEMBL24795917 0.83 ALDH1A1 (0.38) ALDH1A1KMT2AOPRM1OPRD1POLB
SCHEMBL21389498 0.82 KMT2A (0.36) FABP4FABP3L3MBTL1ALDH1A1MAPK1
SCHEMBL26746394 0.82 KMT2A (0.42) FABP4FABP3L3MBTL1ALDH1A1MAPK1
SCHEMBL21389123 0.80 GAA (0.36) FABP4FABP3GAAL3MBTL1ALDH1A1
SCHEMBL24795951 0.78 L3MBTL1 (0.38) GAAL3MBTL1ALDH1A1KMT2ALMNA
SCHEMBL24795899 0.78 PLA2G7 (0.36) FABP4FABP3GAAL3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS CARMOT THERAPEUTICS, INC. 2023-11-09 — — US disclosed
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS CARMOT THERAPEUTICS, INC. 2023-11-09 — — US disclosed
US-11535660-B1 Modulators of G-protein coupled receptors Cannot Therapeutics, Inc. (US) 2022-12-27 — — US disclosed
WO-2019183577-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS CARMOT THERAPEUTICS, INC. (US) 2019-09-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS GIPR, GLP1R, GCGR FABP4 1047/4885FABP3 666/4885GAA 1526/4885
US-11535660-B1 Modulators of G-protein coupled receptors GIPR, GLP1R, GCGR FABP4 1018/4885FABP3 669/4885GAA 1536/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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