Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HEXA | P06865 | 1/20 | 0.33 |
| ▸ | HEXB | P07686 | 1/20 | 0.33 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13291898 | 0.78 | SMN1; SMN2 (0.46) | ALDH1A1MEN1KMT2ARAB9AESR1 | |
| SCHEMBL26744408 | 0.76 | HEXA (0.34) | HEXAHEXB | |
| SCHEMBL21389207 | 0.76 | HEXA (0.34) | HEXAHEXB | |
| SCHEMBL24796129 | 0.76 | HEXA (0.34) | HEXAHEXB | |
| SCHEMBL19755111 | 0.73 | KMT2A (0.35) | MT-CO2ALOX5KMT2ARAB9APOLB | |
| SCHEMBL13291893 | 0.68 | ACHE (0.43) | ALDH1A1 | |
| SCHEMBL17614238 | 0.68 | CYP19A1 (0.38) | HEXAHEXBALDH1A1MEN1KMT2A | |
| SCHEMBL21625395 | 0.67 | LMNA (0.37) | RAB9APOLBLMNA | |
| SCHEMBL7487859 | 0.67 | SMN1; SMN2 (0.50) | ALDH1A1MEN1KMT2ARAB9AESR1 | |
| SCHEMBL13528429 | 0.67 | ALDH1A1 (0.72) | ALDH1A1KDM4EMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183577-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |