Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28439629 | 0.80 | — | — | |
| Bromide SCHEMBL30492612 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL30492650 | 0.77 | — | — | |
| SCHEMBL21587465 | 0.76 | TSHR (0.41) | ALDH1A1TSHRTDP1 | |
| SCHEMBL4546723 | 0.75 | TSHR (0.45) | ALDH1A1TSHRTDP1 | |
| SCHEMBL9750838 | 0.75 | TSHR (0.45) | ALDH1A1TSHRTDP1 | |
| SCHEMBL19389597 | 0.74 | ALDH1A1 (0.39) | ALDH1A1TSHRTDP1 | |
| SCHEMBL4837723 | 0.74 | ALDH1A1 (0.39) | ALDH1A1TSHRTDP1 | |
| SCHEMBL16596099 | 0.72 | TSHR (0.43) | ALDH1A1TSHRTDP1 | |
| SCHEMBL6673656 | 0.72 | TSHR (0.43) | ALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10793605-B2 | Conformationally-preorganized, miniPEG-containing γ-peptide nucleic acids | CARNEGIE MELLON UNIVERSITY (US) | 2020-10-06 | — | — | US | disclosed |
| US-20190292227-A1 | CONFORMATIONALLY-PREORGANIZED, MINIPEG-CONTAINING GAMMA-PEPTIDE NUCLEIC ACIDS | CARNEGIE MELLON UNIVERSITY (US) | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10793605-B2 | Conformationally-preorganized, miniPEG-containing γ-peptide nucleic acids | POLL, PCNA, POLG | ALDH1A1 4289/4885TSHR 1442/4885TDP1 419/4885 |
| US-20190292227-A1 | CONFORMATIONALLY-PREORGANIZED, MINIPEG-CONTAINING GAMMA-PEPTIDE NUCLEIC ACIDS | POLL, PCNA, POLG | ALDH1A1 4116/4885TSHR 1396/4885TDP1 360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.