SCHEMBL21390340

SCHEMBL21390340

C=Cc1ccc2c3ccc(-c4cccc(-c5ccccc5-c5nc(-c6ccccc6)nc(-c6ccccc6)n5)c4)cc3c3ccccc3c2c1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.33
KMT2A Q03164 4/20 0.33
ALDH1A1 P00352 3/20 0.33
MAPT P10636 3/20 0.33
HPGD P15428 3/20 0.33
TSHR P16473 2/20 0.33
ADORA3 P0DMS8 1/20 0.33
ALOX15 P16050 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA2B P29275 1/20 0.33
ADORA1 P30542 1/20 0.33
KDM4E B2RXH2 2/20 0.33
ATM Q13315 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
TP53 P04637 1/20 0.33
NFKB1 P19838 1/20 0.33
MAPK1 P28482 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21390341 0.91 MEN1 (0.35) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL21390343 0.91 PTGS2 (0.38) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL21390580 0.91 MEN1 (0.37) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL16641417 0.88 MEN1 (0.41) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL21390522 0.87 MEN1 (0.40) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL20620351 0.85 MEN1 (0.39) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL20620042 0.85 MEN1 (0.39) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL21390638 0.85 ALOX5 (0.34) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL21390337 0.85 MEN1 (0.44) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL20619989 0.84 GP6 (0.38) MEN1KMT2AALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3547384-A1 HIGH POLYMER, MIXTURE CONTAINING SAME, COMPOSITION, ORGANIC ELECTRONIC COMPONENT, AND MONOMER FOR POLYMERIZATION Guangzhou Chinaray Optoelectronic Materials Ltd. (CN) 2019-10-02 EP disclosed
US-20190292309-A1 HIGH POLYMER, MIXTURE CONTAINING SAME, COMPOSITION, ORGANIC ELECTRONIC COMPONENT, AND MONOMER FOR POLYMERIZATION GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) 2019-09-26 US disclosed