SCHEMBL21390521

SCHEMBL21390521

C=Cc1ccc2c3ccc(-c4cc(-c5ccccc5)nc(-c5ccccc5)c4)cc3c3ccccc3c2c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.37
CYP19A1 P11511 1/20 0.37
MEN1 O00255 5/20 0.37
KMT2A Q03164 5/20 0.37
PTGES O14684 1/20 0.36
DHODH Q02127 1/20 0.36
PTGS2 P35354 1/20 0.36
ESRRB O95718 1/20 0.35
ESR1 P03372 1/20 0.35
ESRRA P11474 1/20 0.35
ESR2 Q92731 1/20 0.35
RAB9A P51151 1/20 0.35
HPGD P15428 3/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
ALDH1A1 P00352 2/20 0.35
ADORA2A P29274 1/20 0.35
ADORA1 P30542 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MAPT P10636 2/20 0.35
NTSR1 P30989 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21390339 0.96 PTGS2 (0.39) ACHECYP19A1MEN1KMT2APTGES
SCHEMBL21390348 0.90 DHODH (0.39) CYP19A1MEN1KMT2ADHODHHPGD
SCHEMBL21390638 0.90 ALOX5 (0.34) ACHEMEN1KMT2APTGESDHODH
SCHEMBL21390520 0.88 MEN1 (0.45) ACHEMEN1KMT2APTGESDHODH
SCHEMBL21390337 0.86 MEN1 (0.44) MEN1KMT2APTGESDHODHPTGS2
SCHEMBL16641364 0.86 ACHE (0.47) ACHECYP19A1MEN1KMT2ADHODH
SCHEMBL17343939 0.84 CYP19A1 (0.50) ACHECYP19A1MEN1KMT2ADHODH
SCHEMBL17343956 0.84 CYP19A1 (0.50) ACHECYP19A1MEN1KMT2ADHODH
SCHEMBL19501127 0.84 CYP19A1 (0.50) ACHECYP19A1MEN1KMT2ADHODH
SCHEMBL21390341 0.83 MEN1 (0.35) ACHEMEN1KMT2APTGESDHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190292309-A1 HIGH POLYMER, MIXTURE CONTAINING SAME, COMPOSITION, ORGANIC ELECTRONIC COMPONENT, AND MONOMER FOR POLYMERIZATION GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) 2019-09-26 US disclosed