SCHEMBL21390585

SCHEMBL21390585

C=CCc1ccc(-c2ccc(-c3cc(-c4ccccc4)cc(-c4ccc(-c5nc(-c6ccccc6)nc(-c6ccccc6)n5)cc4)c3)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDH1 O75874 1/20 0.43
KMT2A Q03164 7/20 0.42
MAPT P10636 7/20 0.42
MEN1 O00255 6/20 0.42
HPGD P15428 4/20 0.42
ALDH1A1 P00352 3/20 0.42
POLB P06746 3/20 0.40
PDE4B Q07343 2/20 0.40
ADORA3 P0DMS8 1/20 0.40
ADORA2A P29274 1/20 0.40
ADORA2B P29275 1/20 0.40
ADORA1 P30542 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
PTGS2 P35354 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
GAA P10253 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
MAPK1 P28482 1/20 0.39
NTSR1 P30989 1/20 0.39
RXRA P19793 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21390641 1.00 IDH1 (0.43) IDH1KMT2AMAPTMEN1HPGD
SCHEMBL21390739 0.95 PTGS2 (0.43) IDH1KMT2AMAPTMEN1HPGD
SCHEMBL21390737 0.89 MAPT (0.41) MAPTPTGS2GAASMN1; SMN2MAPK1
SCHEMBL21390586 0.87 TDP1 (0.41) IDH1KMT2AMAPTMEN1HPGD
SCHEMBL21390740 0.84 CYP19A1 (0.44) KMT2AMAPTMEN1HPGDALDH1A1
SCHEMBL1533221 0.84 TAAR1 (0.50) KMT2AMAPTMEN1HPGDALDH1A1
SCHEMBL21390642 0.83 PRKCI (0.43) MAPTPTGS2GAASMN1; SMN2
SCHEMBL21390732 0.83 PRKCI (0.43) MAPTPTGS2GAASMN1; SMN2
SCHEMBL21390604 0.82 PTGS2 (0.48) IDH1KMT2AMAPTMEN1HPGD
SCHEMBL21390636 0.82 CYP2A6 (0.46) KMT2AMAPTMEN1HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190292309-A1 HIGH POLYMER, MIXTURE CONTAINING SAME, COMPOSITION, ORGANIC ELECTRONIC COMPONENT, AND MONOMER FOR POLYMERIZATION GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) 2019-09-26 US disclosed