SCHEMBL21390737

SCHEMBL21390737

C=CCc1ccc(-c2cc(-c3ccccc3)cc(-c3ccc(-c4cccc(-c5cccc(-c6nc(-c7ccncc7)nc(-c7ccncc7)n6)c5)c4)cc3)c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.41
SMN1; SMN2 Q16637 3/20 0.40
NPC1 O15118 1/20 0.40
NFKB1 P19838 1/20 0.40
RAB9A P51151 1/20 0.40
NFKB2 Q00653 1/20 0.40
RELA Q04206 1/20 0.40
HSD17B10 Q99714 1/20 0.40
PRKCI P41743 1/20 0.40
GAA P10253 1/20 0.40
CYP17A1 P05093 3/20 0.40
CYP3A4 P08684 3/20 0.40
CYP11B1 P15538 3/20 0.40
CYP11B2 P19099 3/20 0.40
CYP19A1 P11511 2/20 0.40
NOTUM Q6P988 1/20 0.40
PTGS2 P35354 1/20 0.39
HTR6 P50406 1/20 0.38
MAPK13 O15264 1/20 0.38
GCGR P47871 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21390642 0.96 PRKCI (0.43) MAPTSMN1; SMN2NPC1NFKB1RAB9A
SCHEMBL21390732 0.96 PRKCI (0.43) MAPTSMN1; SMN2NPC1NFKB1RAB9A
SCHEMBL21390739 0.93 PTGS2 (0.43) MAPTSMN1; SMN2CYP3A4PTGS2MAPK1
SCHEMBL21390285 0.90 PRKCI (0.47) MAPTSMN1; SMN2NPC1NFKB1RAB9A
SCHEMBL21390641 0.89 IDH1 (0.43) MAPTSMN1; SMN2GAAPTGS2TSHR
SCHEMBL21390585 0.89 IDH1 (0.43) MAPTSMN1; SMN2GAAPTGS2TSHR
SCHEMBL21390740 0.87 CYP19A1 (0.44) MAPTSMN1; SMN2NPC1RAB9AHSD17B10
SCHEMBL21390636 0.86 CYP2A6 (0.46) MAPTSMN1; SMN2NPC1RAB9AHSD17B10
SCHEMBL21481328 0.84 NOTUM (0.56) MAPTSMN1; SMN2NPC1NFKB1RAB9A
SCHEMBL17720918 0.84 NOTUM (0.56) MAPTSMN1; SMN2NPC1NFKB1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190292309-A1 HIGH POLYMER, MIXTURE CONTAINING SAME, COMPOSITION, ORGANIC ELECTRONIC COMPONENT, AND MONOMER FOR POLYMERIZATION GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) 2019-09-26 US disclosed