Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CCR9 | P51686 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.30 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21390773 | 0.87 | MEN1 (0.35) | MEN1KMT2APOLBLMNACCR9 | |
| SCHEMBL21391128 | 0.85 | MEN1 (0.36) | MEN1KMT2APOLBLMNAENPP2 | |
| SCHEMBL21390718 | 0.79 | MEN1 (0.42) | MEN1KMT2APOLBLMNAENPP2 | |
| SCHEMBL21390950 | 0.77 | CYP11B2 (0.36) | HDAC1 | |
| SCHEMBL16084207 | 0.75 | RPS6KA3 (0.36) | MEN1KMT2ALMNACCR9TP53 | |
| SCHEMBL21391129 | 0.74 | MEN1 (0.37) | MEN1KMT2APOLBTLR7LMNA | |
| SCHEMBL21390723 | 0.74 | — | — | |
| SCHEMBL21390751 | 0.74 | CCR9 (0.32) | CCR9HDAC1HDAC6 | |
| SCHEMBL21390772 | 0.71 | MEN1 (0.36) | MEN1KMT2APOLBLMNAENPP2 | |
| SCHEMBL17481338 | 0.70 | RPS6KA3 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |