Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 7/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391128 | 0.90 | MEN1 (0.36) | MEN1KMT2AENPP2POLBRORC | |
| SCHEMBL21391126 | 0.86 | MEN1 (0.42) | MEN1KMT2AENPP2TP53POLB | |
| SCHEMBL21390772 | 0.81 | MEN1 (0.36) | MEN1KMT2AENPP2POLBRORC | |
| SCHEMBL16084162 | 0.75 | SMN1; SMN2 (0.39) | MEN1KMT2ATP53RORCKDM4E | |
| SCHEMBL21390722 | 0.74 | MEN1 (0.35) | MEN1KMT2AENPP2TP53POLB | |
| SCHEMBL16084158 | 0.71 | MAPK14 (0.43) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL21390848 | 0.71 | RORC (0.33) | TP53POLBRORCALDH1A1 | |
| SCHEMBL21390963 | 0.71 | PDE2A (0.31) | — | |
| SCHEMBL21390853 | 0.70 | RORC (0.32) | RORC | |
| SCHEMBL21390829 | 0.70 | CNR2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |