Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21390915 | 0.87 | CES1 (0.33) | HDAC6APEX1CES1NCEH1DAGLA | |
| SCHEMBL21391128 | 0.85 | MEN1 (0.36) | MEN1KMT2ALMNAPOLBENPP2 | |
| SCHEMBL21390773 | 0.85 | MEN1 (0.35) | MEN1KMT2ALMNAPOLBHDAC6 | |
| SCHEMBL21391129 | 0.81 | MEN1 (0.37) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL21391134 | 0.81 | RORC (0.33) | ALDH1A1SMN1; SMN2MAPTMAPK1ACSS2 | |
| SCHEMBL21390828 | 0.80 | — | — | |
| SCHEMBL20624604 | 0.78 | ACSS2 (0.36) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL19277969 | 0.78 | ACSS2 (0.36) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL21391126 | 0.76 | MEN1 (0.42) | MEN1KMT2ALMNAMAPTPOLB | |
| SCHEMBL21390829 | 0.75 | CNR2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |