Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 1/20 | 0.32 |
| ▸ | CCND3 | P30281 | 1/20 | 0.32 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.31 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391027 | 0.97 | CDK4 (0.32) | CDK4CCND1CCND3CDK6HDAC1 | |
| SCHEMBL21391080 | 0.92 | CDK4 (0.31) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL21390826 | 0.83 | CACNA1H (0.35) | CDK4CCND1CCND3CDK6HDAC1 | |
| SCHEMBL23132029 | 0.82 | HDAC1 (0.33) | CDK4CCND1CCND3CDK6HDAC1 | |
| SCHEMBL21390898 | 0.81 | HDAC1 (0.32) | CDK4CCND1CCND3CDK6HDAC1 | |
| SCHEMBL21391103 | 0.81 | HDAC1 (0.33) | CDK4CCND1CCND3CDK6HDAC1 | |
| SCHEMBL21390672 | 0.81 | BRD4 (0.34) | CDK4CCND1CCND3CDK6HDAC1 | |
| SCHEMBL21390935 | 0.80 | HDAC1 (0.33) | CDK4CCND1CCND3CDK6HDAC1 | |
| SCHEMBL21354572 | 0.79 | IDH1 (0.32) | CDK4CCND1CCND3CDK6 | |
| SCHEMBL21390822 | 0.77 | CYP19A1 (0.33) | CDK4CCND1CCND3CDK6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |