Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 2/20 | 0.53 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMO | O15229 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | USP7 | Q93009 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21142186 | 1.00 | HSD17B1 (0.53) | HSD17B1HSD17B2MAPK1ALDH1A1KMO | |
| SCHEMBL19933811 | 0.95 | HSD17B1 (0.53) | HSD17B1HSD17B2MAPK1ALDH1A1NFKB1 | |
| SCHEMBL18015263 | 0.89 | MAPK1 (0.57) | HSD17B1HSD17B2MAPK1ALDH1A1NFKB1 | |
| SCHEMBL19833695 | 0.87 | ALDH1A1 (0.46) | HSD17B1HSD17B2MAPK1ALDH1A1NFKB1 | |
| SCHEMBL18015479 | 0.87 | HSD17B1 (0.59) | HSD17B1HSD17B2KMONFKB1RAB9A | |
| SCHEMBL19933600 | 0.86 | ALDH1A1 (0.52) | HSD17B1HSD17B2MAPK1ALDH1A1LDHA | |
| SCHEMBL23239870 | 0.85 | HSD17B1 (0.57) | HSD17B1HSD17B2KMOLDHAHPGDS | |
| SCHEMBL19794434 | 0.85 | HSD17B1 (0.57) | HSD17B1HSD17B2KMOLDHAHPGDS | |
| SCHEMBL23956290 | 0.85 | HSD17B1 (0.57) | HSD17B1HSD17B2KMOLDHAHPGDS | |
| SCHEMBL23239937 | 0.85 | KDM1A (0.47) | HSD17B1HSD17B2MAPK1ALDH1A1KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11917903-B2 | Metal complexes | UDC IRELAND LIMITED (IE) | 2024-02-27 | — | — | US | disclosed |
| US-11917903-B2 | Metal complexes | UDC IRELAND LIMITED (IE) | 2024-02-27 | — | — | US | disclosed |
| US-20210111345-A1 | METAL COMPLEXES | UDC IRELAND LIMITED (IE) | 2021-04-15 | — | — | US | disclosed |
| WO-2019179909-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-09-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210111345-A1 | METAL COMPLEXES | NCLN, BICRA, AP3M1 | HSD17B1 4561/4885HSD17B2 4525/4885MAPK1 4348/4885 |
| US-11917903-B2 | Metal complexes | NCLN, BICRA, AP3M1 | HSD17B1 4561/4885HSD17B2 4525/4885MAPK1 4348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.