Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.31 |
| ▸ | MTOR | P42345 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | VDR | P11473 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.30 |
| ▸ | OGFRL1 | Q5TC84 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21354667 | 0.82 | GAA (0.35) | PLA2G1BTSHRHSD17B10ATG4BMAPT | |
| SCHEMBL30315701 | 0.82 | GAA (0.35) | PLA2G1BTSHRHSD17B10ATG4BMAPT | |
| SCHEMBL21390682 | 0.80 | JAK1 (0.32) | PLA2G1BTSHRHSD17B10ATG4B | |
| SCHEMBL21390969 | 0.75 | TNF (0.38) | MAPTOPRM1OPRD1OPRK1OGFRL1 | |
| SCHEMBL21354732 | 0.70 | EGFR (0.34) | PLA2G1BTSHRHSD17B10ATG4BMAPT | |
| SCHEMBL21391028 | 0.69 | MAPT (0.30) | MAPT | |
| SCHEMBL23678917 | 0.65 | CYP11B2 (0.33) | — | |
| SCHEMBL21354557 | 0.64 | KDM4E (0.40) | OPRM1OPRD1OPRK1OGFRL1 | |
| SCHEMBL29701144 | 0.64 | KDM4E (0.40) | OPRM1OPRD1OPRK1OGFRL1 | |
| SCHEMBL21354658 | 0.62 | PLA2G1B (0.35) | PLA2G1BTSHRHSD17B10ATG4BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |