Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21354742 | 0.73 | EGFR (0.33) | — | |
| SCHEMBL21391029 | 0.69 | PLA2G1B (0.33) | MAPT | |
| SCHEMBL21390969 | 0.69 | TNF (0.38) | MAPT | |
| SCHEMBL21391078 | 0.64 | KDM4E (0.33) | — | |
| SCHEMBL21390933 | 0.63 | CDK4 (0.32) | — | |
| SCHEMBL21391027 | 0.62 | CDK4 (0.32) | — | |
| SCHEMBL21390815 | 0.62 | HDAC1 (0.33) | — | |
| SCHEMBL21354724 | 0.61 | EGFR (0.33) | — | |
| SCHEMBL21354572 | 0.61 | IDH1 (0.32) | — | |
| SCHEMBL21354589 | 0.59 | ALK (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |