Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | PRPS1 | P60891 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HCAR1 | Q9BXC0 | 5/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21025784 | 0.85 | HSD17B10 (0.44) | ALDH1A1LMNASMN1; SMN2HPGDNPSR1 | |
| SCHEMBL18731876 | 0.79 | DRD2 (0.42) | ALDH1A1LMNASMN1; SMN2HPGDGAA | |
| SCHEMBL16656627 | 0.78 | HPGD (0.54) | ALDH1A1LMNASMN1; SMN2HPGDNPSR1 | |
| SCHEMBL22239420 | 0.78 | SCN9A (0.54) | ATM | |
| SCHEMBL2850424 | 0.77 | LMNA (0.53) | ALDH1A1LMNASMN1; SMN2HPGDNPSR1 | |
| SCHEMBL17678351 | 0.77 | GAA (0.47) | ALDH1A1LMNAHPGDGAAHTT | |
| SCHEMBL18474192 | 0.77 | HSD17B10 (0.47) | ALDH1A1HPGDGAAIDO1PRPS1 | |
| SCHEMBL17678098 | 0.77 | GAA (0.47) | ALDH1A1HPGDGAAHSD17B10HCAR1 | |
| SCHEMBL13135673 | 0.76 | USP2 (0.60) | ALDH1A1LMNASMN1; SMN2HPGDNPSR1 | |
| SCHEMBL18136684 | 0.74 | GAA (0.50) | ALDH1A1LMNAHPGDGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |