Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 7/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 9/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391035 | 0.88 | HDAC1 (0.35) | HDAC1 | |
| SCHEMBL21391063 | 0.85 | HDAC1 (0.36) | HDAC1CYP11B2CYP11B1CYP19A1 | |
| SCHEMBL21391060 | 0.85 | HDAC1 (0.36) | HDAC1CYP11B2CYP11B1CYP19A1 | |
| SCHEMBL21391178 | 0.84 | HDAC1 (0.30) | HDAC1 | |
| SCHEMBL21391075 | 0.81 | — | — | |
| SCHEMBL21391067 | 0.79 | KDM4E (0.32) | — | |
| SCHEMBL18792000 | 0.78 | CYP11B2 (0.35) | CYP11B2CYP11B1 | |
| SCHEMBL21391006 | 0.75 | CYP11B2 (0.36) | CYP11B2CYP11B1 | |
| SCHEMBL23132031 | 0.75 | CYP11B2 (0.41) | HDAC1CYP11B2CYP11B1CYP19A1 | |
| SCHEMBL21391012 | 0.75 | CYP11B1 (0.32) | CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |