SCHEMBL21391178

SCHEMBL21391178

O=C(CCCCc1nc2c(F)cc(C3CC3)cc2n1C1CCC1)CC(O)(CF)CF

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21391061 0.85 ACSS2 (0.33) HDAC1
SCHEMBL21391066 0.84 HDAC1 (0.35) HDAC1
SCHEMBL21391103 0.79 HDAC1 (0.33) HDAC1
SCHEMBL21391164 0.78 CDK4 (0.35) HDAC1
SCHEMBL18791992 0.78 EGFR (0.33)
SCHEMBL21391035 0.78 HDAC1 (0.35) HDAC1
SCHEMBL21390935 0.77 HDAC1 (0.33) HDAC1
SCHEMBL21391177 0.76 RORC (0.32) HDAC1
SCHEMBL21391027 0.76 CDK4 (0.32) HDAC1
SCHEMBL21390898 0.75 HDAC1 (0.32) HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019183148-A1 KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE KNOPP BIOSCIENCES LLC (US) 2019-09-26 WO disclosed