Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | JAK1 | P23458 | 2/20 | 0.32 |
| ▸ | TYK2 | P29597 | 2/20 | 0.32 |
| ▸ | JAK3 | P52333 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21390808 | 0.87 | JAK2 (0.33) | KDM4EALDH1A1HPGDHIF1AJAK2 | |
| SCHEMBL21390815 | 0.81 | HDAC1 (0.33) | JAK1HDAC1 | |
| SCHEMBL21390810 | 0.79 | CYP19A1 (0.32) | JAK2JAK1TYK2JAK3HDAC1 | |
| SCHEMBL21390935 | 0.78 | HDAC1 (0.33) | HDAC1 | |
| SCHEMBL21390979 | 0.77 | HDAC1 (0.32) | ALDH1A1JAK1HDAC1 | |
| SCHEMBL21391086 | 0.77 | AR (0.33) | KDM4EALDH1A1HPGDHIF1AJAK2 | |
| SCHEMBL21391079 | 0.77 | CYP19A1 (0.32) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL21390892 | 0.77 | KDM4E (0.33) | KDM4EALDH1A1HPGDHIF1AJAK2 | |
| SCHEMBL23132029 | 0.75 | HDAC1 (0.33) | KDM4EALDH1A1HPGDHDAC1 | |
| SCHEMBL21391159 | 0.74 | SMN1; SMN2 (0.35) | KDM4EALDH1A1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |