Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391159 | 0.86 | SMN1; SMN2 (0.35) | HDAC1ALDH1A1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL21390815 | 0.79 | HDAC1 (0.33) | HDAC1JAK1 | |
| SCHEMBL21390682 | 0.78 | JAK1 (0.32) | JAK1 | |
| SCHEMBL21391078 | 0.77 | KDM4E (0.33) | HDAC1JAK1ALDH1A1 | |
| SCHEMBL21390890 | 0.77 | PLA2G1B (0.33) | HDAC1JAK1 | |
| SCHEMBL21390924 | 0.76 | HTR3A (0.34) | JAK1ALDH1A1 | |
| SCHEMBL21390819 | 0.75 | CNR2 (0.32) | HDAC1JAK1 | |
| SCHEMBL21391086 | 0.75 | AR (0.33) | HDAC1JAK1ALDH1A1 | |
| SCHEMBL21390892 | 0.75 | KDM4E (0.33) | JAK1ALDH1A1 | |
| SCHEMBL23132031 | 0.74 | CYP11B2 (0.41) | HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |