Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 6/20 | 0.33 |
| ▸ | IDH1 | O75874 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21390914 | 0.97 | AGTR1 (0.35) | AGTR1AGTR2TBXA2RIDH1HDAC3 | |
| SCHEMBL21390871 | 0.81 | — | — | |
| SCHEMBL21354576 | 0.79 | IDH1 (0.35) | IDH1 | |
| SCHEMBL21390862 | 0.77 | AGTR1 (0.37) | AGTR1AGTR2TBXA2RIDH1HDAC3 | |
| SCHEMBL21390717 | 0.74 | ACACB (0.31) | — | |
| SCHEMBL23329655 | 0.72 | TBXA2R (0.33) | TBXA2R | |
| SCHEMBL26008187 | 0.71 | IDH1 (0.35) | IDH1 | |
| SCHEMBL21390703 | 0.71 | — | — | |
| SCHEMBL21391115 | 0.70 | — | — | |
| SCHEMBL21391166 | 0.68 | HDAC3 (0.31) | HDAC3HDAC4HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |