Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 11/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | CCR3 | P51677 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21390715 | 0.89 | HDAC3 (0.31) | HDAC3PTGS1HDAC4HDAC1HDAC2 | |
| SCHEMBL21391109 | 0.80 | — | — | |
| SCHEMBL21390708 | 0.80 | — | — | |
| SCHEMBL21390914 | 0.79 | AGTR1 (0.35) | AGTR1AGTR2TBXA2RHDAC3PTGS1 | |
| SCHEMBL21390788 | 0.78 | — | — | |
| SCHEMBL21354678 | 0.78 | IDH1 (0.35) | TBXA2RCYP11B1CYP11B2IDH1 | |
| SCHEMBL21391090 | 0.77 | AGTR1 (0.35) | AGTR1AGTR2TBXA2RHDAC3PTGS1 | |
| SCHEMBL21390705 | 0.72 | — | — | |
| SCHEMBL21390709 | 0.71 | HDAC3 (0.31) | HDAC3PTGS1HDAC4HDAC1HDAC2 | |
| SCHEMBL21391175 | 0.70 | ACACB (0.33) | AGTR1AGTR2HDAC3PTGS1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |