Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391166 | 0.80 | HDAC3 (0.31) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL21390895 | 0.80 | GPR119 (0.31) | — | |
| SCHEMBL21390717 | 0.80 | ACACB (0.31) | ACACB | |
| SCHEMBL18791848 | 0.78 | ACACB (0.36) | ACACBCYP3A4KCNH2NR1H4 | |
| SCHEMBL21390802 | 0.78 | CYP11B1 (0.30) | — | |
| SCHEMBL21390930 | 0.78 | HDAC3 (0.30) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL21390715 | 0.77 | HDAC3 (0.31) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL21390811 | 0.76 | AR (0.32) | — | |
| SCHEMBL21391068 | 0.76 | PDE2A (0.30) | — | |
| SCHEMBL21390884 | 0.73 | BRD4 (0.33) | HDAC3HDAC4HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |