Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10292049 | 0.91 | ALDH1A1 (0.46) | ALDH1A1LMNAHSD17B10CA12CA1 | |
| SCHEMBL13479942 | 0.84 | CHRNB2 (0.45) | ALDH1A1LMNAHSD17B10CA12CA1 | |
| SCHEMBL15359184 | 0.83 | MGAM (0.41) | ALDH1A1LMNAHSD17B10CA12CA1 | |
| SCHEMBL254842 | 0.82 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10CA12CA1 | |
| SCHEMBL19925012 | 0.81 | CA12 (0.37) | ALDH1A1LMNAHSD17B10CA12CA1 | |
| SCHEMBL26742778 | 0.81 | CHRNB2 (0.36) | CHRNB2CHRNA4CHRNB4CHRNA3CHRM1 | |
| SCHEMBL13404999 | 0.81 | ALDH1A1 (0.41) | ALDH1A1LMNAHSD17B10CA12CA1 | |
| SCHEMBL995722 | 0.80 | LMNA (0.40) | ALDH1A1LMNAHSD17B10CA12CA1 | |
| Ammonia Solution, Strong SCHEMBL29011843 | 0.80 | ALDH1A1 (0.40) | ALDH1A1LMNAHSD17B10CA12CA1 | |
| SCHEMBL9256154 | 0.80 | CHRNB2 (0.55) | ALDH1A1LMNAHSD17B10CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183270-A1 | PUROMYCIN-BASED PROBES AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-09-26 | — | — | WO | disclosed |