Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17450061 | 0.85 | MMP8 (0.37) | ALDH1A1KDM4EPKMTHRBGAA | |
| SCHEMBL27693596 | 0.78 | KDM4C (0.47) | ALDH1A1LMNAHSD17B10KDM4EPKM | |
| SCHEMBL13278855 | 0.78 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10KDM4EPKM | |
| SCHEMBL7773591 | 0.76 | GAA (0.39) | ALDH1A1LMNAHSD17B10KDM4EPKM | |
| SCHEMBL7773594 | 0.76 | ALOX15 (0.44) | ALDH1A1LMNAHSD17B10KDM4EPKM | |
| Hydrochloric Acid SCHEMBL27676717 | 0.76 | KDM4C (0.46) | ALDH1A1LMNAHSD17B10KDM4EPKM | |
| SCHEMBL10623261 | 0.75 | GAA (0.42) | ALDH1A1LMNAHSD17B10KDM4EPKM | |
| SCHEMBL2757934 | 0.74 | GAA (0.46) | ALDH1A1LMNAHSD17B10KDM4EPKM | |
| SCHEMBL9476910 | 0.74 | GAA (0.46) | ALDH1A1LMNAHSD17B10KDM4EPKM | |
| SCHEMBL9117578 | 0.73 | GAA (0.44) | ALDH1A1LMNAHSD17B10KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183270-A1 | PUROMYCIN-BASED PROBES AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-09-26 | — | — | WO | disclosed |